Low Tidal Volume Ventilation: Trust but Verify

Low Tidal Volume Ventilation: Trust but Verify.

Despite affecting an estimated 4 –7% of patients in the ICU and having a high mortality rate, there are currently a limited number of therapeutic options to treat patients with ARDS.1,2 ARMA, the landmark ARDSnet trial in 2000, established the concept of lungprotective ventilation, where subjects with ARDS receiving mechanical ventilation were randomly assigned to a set tidal volume (VT) of eit...

Intraoperative low-tidal-volume ventilation.

Trust but Pre-Verify?

Governments should be uncompromising in jointly seeking both information and privacy goals for the data that is in their stewardship. The GAO’s 2001 report on Record Linkage and Privacy places a combined high priority on information gains and privacy issues–and presents this position in contrast to an alternative “zero-sum approach” that conceptualizes privacy and information mainly, or only in...

Underwriting Ventures : Trust but Verify

What determines the choice of a production technology within a country? While there could be many factors, the e¢ ciency of the country’s …nancial system may play a signi…cant role. To address this question, a dynamic contract model is embedded into a general equilibrium setting with competitive intermediation. The ability of an intermediary to monitor the activity of a …rm plays an important r...

DNA Repair: Trust but Verify

Damage recognition is a key initial step in DNA repair. A recent study puts to rest the debate of whether XPD helicase 'verifies' the appropriateness of the DNA damage to be mended by the nucleotide excision repair machinery.